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目的比较宫颈扩张球囊及地诺前列酮栓(欣普贝生)用于妊娠期糖尿病(GDM)引产的有效性和安全性。方法 150例足月GDM初产妇采用随机数字表法分成治疗组与对照组,各75例,治疗组患者进行COOK宫颈扩张球囊促宫颈成熟治疗,对照组患者进行阴道后穹窿放置欣普贝生促宫颈成熟治疗。对两种方法的促宫颈成熟效果、临产时间、分娩方式、血糖变化及不良反应进行分析比较。结果治疗组促宫颈成熟的效果及阴道分娩率与对照组相近(P>0.05),不良反应低于对照组,差异有统计学意义(P<0.05)。结论对足月GDM初产妇采用COOK宫颈扩张球囊及欣普贝生均可以有效促进宫颈成熟,COOK宫颈扩张球囊的不良反应少,值得推广。
Objective To compare the effectiveness and safety of cervical dilation balloon and dinoprostone suppository (Xin P bei sheng) for induction of gestational diabetes mellitus (GDM). Methods A total of 150 full-term GDM primiparae were divided into treatment group and control group by random number table method, 75 cases in each group. The patients in the treatment group were treated with COOK cervical dilatation balloon to promote cervical ripening, while the control group were treated with vaginal posterior fornix Promote cervical maturation treatment. The two methods of promoting cervical maturation effect, labor time, mode of delivery, blood glucose changes and adverse reactions were analyzed and compared. Results The effect of cervical ripening and vaginal delivery in the treatment group were similar to those in the control group (P> 0.05). The adverse reactions were lower than those in the control group (P <0.05). Conclusions The use of COOK cervical dilatation balloon and Xinpbeibei for full-term GDM primipara can effectively promote cervical ripening, and the adverse reactions of COOK cervical dilation balloon are worthy to be popularized.