Fas/FasL在辐射诱导胆管癌细胞凋亡发生和调控中的作用

来源 :中国保健营养(中旬刊) | 被引量 : 0次 | 上传用户:mitudierwa
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
胆管癌发病率逐年升高,但研究进展缓慢,发病机理远未明了,早期诊断困难,外科治疗棘手,放化疗均不敏感,预后差,是肿瘤临床的一大难题.但随着细胞凋亡的研究的进一步深入,给胆管癌的诊治带来了希望.Fas/FasL系统是凋亡发生和调控的重要因子.放疗对肿瘤的作用主要是诱导其细胞凋亡.而在辐射诱导胆管癌细胞的凋亡中弄清Fas/FasL对其调控机制对胆管癌的发生发展,诊断治疗及预后都有重要意义,本文结合有关文献作一综述.
其他文献
励磁涌流识别是变压器微机差动保护中的关键问题.在综合考虑多方面因素的前提下,提出了一种基于改进型动态结构神经网络的涌流识别新方法.其主要思想为在采用多层前向反馈传
福岛这次核泄漏事件引发了人们对核电安全性的空前关注,即前苏联切尔诺贝利核电站事故后,再一次引发了人们对核电站安全的担忧。众所周知,这次福岛核电站泄漏,不是人为的操作
AIM: To investigate the bactericidal and anti-adhesive properties of 25 plants against Helicobacter pylori (H pylori).METHODS: Twenty-five plants were boiled in
Solitary non-parasitic liver cysts are being increasingly diagnosed due to the increased use of abdominal sonography. The majority of solitary liver cysts are a
Background Activation and proliferation of hepatic stellate cells (HSC) is essentially involved in the development and progression of hepatic fibrosis. The most
AIM: To investigate the role of overexpression of Bax in apoptotic pathways and the response of human hepatocellular cancer (HCC)-9204 cells to cell death induc
目的分析人工流产后继发不孕症的原因,探讨有效的诊治手段。方法选取本院近年来收治的55例人工流产后继发不孕症患者作为研究对象,给予B超检查、常规妇科诊断、白带常规检查
Background Due to the controversy of the oral glucose tolerance test (OGTT), diagnostic criteria for gestational diabetes mellitus (GDM) in the world and resear
The etiology of inflammatory bowel disease is multifacto-rial and appears to combine both genetic and environmental factors. We experienced here a rare occurren
AIM: To investigate effects of ischemic pre-conditioning on the liver endogenous oxidant-antioxidant system during ischemia/reperfusion injury.METHODS: Twenty-f