论文部分内容阅读
过去30年中感染性心内膜炎(简称心内膜炎)的临床表现、微生物学以及治疗学方面发生了戏剧般的变化。以往本病“经典”临床表现──发热、“杂音性质的改变”、脾大、周围血管栓塞和血培养阳性──现已不常见。事实上,今天如按上述表现来诊断心内膜炎,90％要失败。引起心内膜炎变化的因素有:风湿性和梅毒性心脏病日益减少;风湿性、先天性和动脉硬化性心脏病者的寿命已较前延长;青霉素和其他抗菌药物的应用增加;人们患病后多及早治疗;心脏外科、静脉滴注高营养物
The dramatic changes in the clinical presentation, microbiology, and therapeutics of infective endocarditis (referred to as endocarditis) have occurred over the past 30 years. The past clinical manifestations of this disease, “classic” ─ ─ fever, “changes in the nature of noise”, splenomegaly, peripheral vascular embolism and positive blood culture ─ ─ is now uncommon. In fact, 90% of patients failing to diagnose endocarditis as of today. Causes of endocarditis changes are: rheumatic and syphilitic heart disease is diminishing; rheumatic, congenital and atherosclerotic heart disease has been extended life expectancy; increased use of penicillin and other antibiotics; people suffering from Early treatment after illness; cardiac surgery, intravenous infusion of high nutrients