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目的:探讨心包积液对慢性心力衰竭的预后的影响。方法:以683例心力衰竭的患者作为研究对象,采用超声心动图对心包积液进行半定量分析。对其中118例心包积液患者和472例无心包积液患者进行随访,使用单因素和多因素统计学方法,分析心包积液对心力衰竭的预后的影响。结果:随访病例中,40例失访,226例死亡。肾小球滤过率[OR=1.013,95%CI(1.005,1.026),P=0.02],收缩压[OR=1.02,95%CI(1.00,1.03),P=0.015],左室射血分数[OR=1.08,95%CI(1.04,1.12),P<0.001]和糖尿病[OR=2.53,95%CI(0.99,6.44),P<0.001],为心力衰竭预后的独立危险因素。慢性心力衰竭生存率随左室射血分数的改善而增加,与是否存在心包积液无关。结论:心包积液存在不增加慢性心力衰竭的病死率。
Objective: To investigate the effect of pericardial effusion on the prognosis of chronic heart failure. Methods: A total of 683 patients with heart failure were enrolled in this study. Semi-quantitative analysis of pericardial effusion was performed by echocardiography. Among them, 118 cases of pericardial effusion and 472 cases of pericardial effusion were followed up, and the influence of pericardial effusion on the prognosis of heart failure was analyzed by univariate and multivariate statistical methods. Results: Among the follow-up cases, 40 were lost and 226 died. Glomerular filtration rate [OR = 1.013, 95% CI (1.005, 1.026), P = 0.02], systolic blood pressure [OR = 1.02, 95% CI (1.00, 1.03), P = 0.015] Score [OR = 1.08,95% CI (1.04,1.12), P <.001] and diabetes (OR = 2.53, 95% CI, 0.99, 6.44, P <0.001) were independent risk factors for the prognosis of heart failure. Chronic heart failure survival rate increased with the improvement of left ventricular ejection fraction, regardless of the presence or absence of pericardial effusion. Conclusion: Pericardial effusion does not increase the mortality rate of chronic heart failure.