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目的了解温州地区脂肪肝流行特征,对相关危险因素进行分析。方法收集2009年在温州医学院附属第一医院体检中心接受体检的人员,随机选取经B超或CT诊断为脂肪肝患者208例为病例组,随机选取188名无脂肪肝者为对照组,自行设计调查问卷进行调查问卷。相关数据用SPSS 13.0软件包进行处理。结果 4219名体检人员中,脂肪肝患病数为878例,患病率为20.81%,男性患病率大于女性患病率(χ2=248.2,P<0.01);脂肪肝随年龄的增加总体呈上升趋势。单因素分析示脂肪肝组超重肥胖、中心性肥胖、高血压、高收缩压、高舒张压、IFG、糖尿病、高甘油三酯血症、高胆固醇血症、低HDL-C血症、高ALT血症、高尿酸血症、代谢综合征、腰臀比超标高于非脂肪肝组。多因素Logistic回归分析,示腰臀比超标、高血压、超重肥胖、高甘油三酯血症、高ALT为脂肪肝的独立危险因素,而粗粮(≥3次/w)、经常锻炼、天天饮酒为脂肪肝的保护因素。结论温州市体检人员脂肪肝患病率高,肥胖及其相关的多元代谢紊乱与脂肪肝的关系密切。
Objective To understand the prevalence of fatty liver in Wenzhou and to analyze the related risk factors. Methods A total of 208 patients with fatty liver diagnosed by B- or CT were randomly selected as the case group from 2009 to the medical examination center of the First Affiliated Hospital of Wenzhou Medical College. 188 patients without fatty liver were selected as the control group Design a questionnaire to conduct a questionnaire. The data is processed using SPSS 13.0 software package. Results Among 4219 medical staffs, the prevalence of fatty liver was 878, with a prevalence of 20.81%. The prevalence rate of male was higher than that of female (χ2 = 248.2, P <0.01). The fatty liver increased with age Upward trend. Univariate analysis showed overweight and obesity, central obesity, hypertension, high systolic blood pressure, high diastolic blood pressure, IFG, diabetes, hypertriglyceridemia, hypercholesterolemia, low HDL-C, high ALT Hyperlipidemia, hyperuricemia, metabolic syndrome, waist-hip ratio were higher than non-fatty liver group. Multivariate Logistic regression analysis showed that waist-hip ratio exceeded, hypertension, overweight and obesity, hypertriglyceridemia, high ALT were independent risk factors for fatty liver, and coarse grains (≥3 times / w), regular exercise, daily drinking For the protection of fatty liver factors. Conclusion The prevalence of fatty liver in Wenzhou medical staff is high, and obesity and its related multi-metabolic disorders are closely related to fatty liver.