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目的探讨Rh血型系统CE复合抗体的鉴定及其特征。方法对1例抗体筛查试验阳性的患者,做Rh表型分型及直接抗球蛋白试验,采用微柱凝胶卡做抗体鉴定确定抗体的特异性,同时对Rh复合抗体的特征进行文献复习。结果患者Rh表型为DCcEe,血清中存在单一的Rh血型系统CE复合抗体,为抗-ce(抗-f、抗-RH6)复合抗体。结论患者红细胞上缺失ce复合抗原,通过输血或妊娠免疫,产生了针对ce复合抗原的抗-ce复合抗体,而这种抗-ce复合抗体与单纯的c或e抗原均无反应性,只与ce复合抗原有反应性。
Objective To investigate the identification and characteristics of CE complex antibody of Rh blood group system. Methods One patient with positive antibody screening test was used to make Rh phenotype and direct antiglobulin test. The antibody specificity was determined by micro-column gel card, and the literature review of the characteristics of Rh complex antibody . Results The Rh phenotype of patients was DCcEe. There was a single CE antibody in Rh blood group in serum, which was an anti-CE (anti-f, anti-RH6) antibody. CONCLUSIONS: The patient’s erythrocytes are deficient in ce composite antigen and have been immunized with blood transfusions or pregnancies resulting in an anti-ce composite antibody against ce complex antigens that are not reactive with either pure c or e antigens ce composite antigen reactive.