目的　分析超声显像对恶性淋巴瘤脾浸润患者在化疗前后的声像图特征。方法　对 36例恶性淋巴瘤 (其中何杰金病 9例 ,非何杰金淋巴瘤 2 7例 )进行化疗前后的超声检查。结果　化疗前 86 .1 %病例有脾脏肿大 ,所有病例脾内均有低回声病灶。声像图表现可分为三种类型 :1 .结节型 ;2 .弥漫粟粒型 ;3.巨块型。本组以结节型多见 ,占 6 9.4 %。化疗后超声复查 ,大多数病例脾脏缩小 ,脾内浸润病灶消失。结论　超声显像对恶性淋巴瘤脾浸润化疗前的诊断和化疗后的监测具有重要的应用价值 ,可为临床诊断治疗和疗效评价提供无创的简便方法 Objective To analyze the sonographic features of patients with malignant lymphoma with splenic invasion before and after chemotherapy. Methods 36 cases of malignant lymphoma (Hodgkin’s disease in 9 cases, non-Hodgkin’s lymphoma in 27 cases) before and after chemotherapy for ultrasound. Results 86.1% of patients had splenomegaly before chemotherapy and all had hypoechoic lesions in spleen. Ultrasonographic performance can be divided into three types: 1. Nodular; 2. diffuse miliary type; 3. bulky. This group is more common in nodules, accounting for 6 9.4%. Ultrasound after chemotherapy review, most cases of spleen, spleen infiltration lesions disappear. Conclusion Ultrasound imaging has important value in the diagnosis of malignant lymphoma before splenic invasion and after chemotherapy, and provides a noninvasive and convenient method for clinical diagnosis and treatment