论文部分内容阅读
目的 探讨肾痛Ki—67和9H7免疫组化染色的临床意义。方法 采用单克隆抗体Ki—67和9H7对41例肾癌手术标本免疫组化染色对比。结果 肾癌两种抗体染色强度均明显高于正常肾组织(P<0.01),但与肿瘤大小、分期、分级无关.Ki—67染色指数与肿瘤复发密切相关(P<0.01),多因数分析对复发的估价Ki—67染色指数(P=0.005)优于肿瘤大小(P=0.007),分期(P=0.018)和年龄(P=0.023) 结论 9H7染色强弱只在直径小于10cm的肿瘤中与复发有关。
Objective To investigate the clinical significance of immunohistochemical staining of Ki-67 and 9H7 in renal pain. Methods Immunohistochemical staining of 41 cases of renal cell carcinoma with monoclonal antibodies Ki-67 and 9H7 was performed. Results The staining intensity of two antibodies in renal carcinoma was significantly higher than that in normal renal tissue (P <0.01), but not with the size, stage and grade of tumor (P <0.01) .Ki-67 staining index was closely related to tumor recurrence Evaluation of recurrence Ki-67 staining index (P = 0.005) was superior to tumor size (P = 0.007), stage (P = 0.018) and age (P = 0.023) Conclusion 9H7 staining intensity only in tumors less than 10cm in diameter And relapse.