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趋化因子是一组具有趋化作用的细胞因子超家族,通过与特异性受体结合发挥生物学功能。趋化因子受体7与口腔鳞癌的侵袭和淋巴结转移等密切相关,现就趋化因子受体7及其配体的功能以及它们在口腔鳞癌侵袭和淋巴结转移中的作用作一综述。
Chemokines are a group of chemotactic cytokine superfamilies that exert their biological functions by binding to specific receptors. Chemokine receptor 7 is closely related to the invasion and lymph node metastasis of oral squamous cell carcinoma. The function of chemokine receptor 7 and its ligands and their roles in the invasion and lymph node metastasis of oral squamous cell carcinoma are reviewed.