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为了解决烧伤败血症的防治问题,作者进行了中药抗败血症的研究。根据实验室中药抑菌试验的结果,选用对绿脓干菌、金黄色葡萄球菌均有较佳抑菌作用的药物,结合烧伤辩证论治原则,选用金银花、连翘、生地、板兰根、甘草、紫花地丁、淡竹叶、麦冬、知母等九味合成解毒汤1号作为研究方剂。实验室研究采用144只家兔为材料,临床观察结合治疗进行,分为中药组、西药组与中西结合三组。药物和剂量、病人与家兔一致,均按体重计算,金霉素、氯霉素、红霉素及土霉素日用剂量为每公斤40毫克,分为四次口服;多粘菌素,青霉素每日剂量为每公斤4万单位,每6小时肌注1/4量;解毒湯1号每公斤10毫升,分为四次
In order to solve the problem of prevention and treatment of burn sepsis, the author conducted a study of traditional Chinese medicine anti-sepsis. According to the results of laboratory antibacterial test of traditional Chinese medicines, the drugs with better antibacterial activity against P. aeruginosa and Staphylococcus aureus were selected, combined with principles of dialectical treatment of burns, honeysuckle, forsythia, habitat, Banlangen, and licorice were selected. Shiwei Syndrome Detoxification Decoction No.1, such as Viola divaricata, light bamboo, Ophiopogon japonicus and Zhimu, was used as a research prescription. In the laboratory study, 144 rabbits were used as materials for clinical observation combined with treatment, and were divided into Chinese medicine group, western medicine group and three groups of Chinese and Western combinations. Drugs and doses, patients and rabbits are consistent, according to body weight calculation, chlortetracycline, chloramphenicol, erythromycin and oxytetracycline daily dose of 40 mg per kg, divided into four oral; polymyxin, The daily dose of penicillin is 40,000 units per kilogram, 1/4 of intramuscular injection every 6 hours; Detoxification decoction No. 1 is 10 ml per kilogram, divided into four times