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目的探讨不同化疗方案治疗肺癌的成本与效果,从中选出最优化的治疗方案,以指导临床合理用药。方法运用药物经济学成本与效果分析方法,对6种方案治疗肺癌的疗效与成本进行回顾性分析评价。结果各组有效率分别为42.86%,57.69%,44.00%,46.15%,48.39%和37.50%;一个疗程的费用分别为28 849,36 127,30 853,20 732,27 943和12 671元;有效率增加一个百分点,成本分别增加673.10,626.23,701.21,449.23,600.41和442.58元。结论吉西他滨+顺铂治疗肺癌的方案是最合理的方案。
Objective To investigate the cost and effect of different chemotherapy regimens in the treatment of lung cancer and to select the optimal treatment regimen to guide clinical rational drug use. Methods The costs and effects of drug economics were used to evaluate the efficacy and cost of six kinds of regimens in the treatment of lung cancer. Results The effective rates in each group were 42.86%, 57.69%, 44.00%, 46.15%, 48.39% and 37.50% respectively. The cost of one course was 28 849, 36 127, 30 853, 20 732, 27 943 and 12 671 respectively. The effective rate increased by one percentage point, the cost increased by 673.10,626.23, 701.21, 449.23, 600.41 and 442.58 yuan respectively. Conclusion Gemcitabine + cisplatin treatment of lung cancer is the most reasonable program.