论文部分内容阅读
目的研究青春期多囊卵巢综合征(PCOS)胰岛素抵抗与非胰岛素抵抗患者生殖内分泌差异。方法将医院收治的青春期PCOS患者86例作为研究对象,依据胰岛素抵抗(IR)程度划分为IR组(46例)与非IR组(40例),检测2组生殖内分泌指标,包括FSH(促卵泡生成素)、LH(促黄体生成素)、T(睾酮)及SHBG(性激素结合蛋白),比较2组上述指标水平并测定F-G评分(多毛评分)、BMI(体重指数)及WHR(腰臀围比值)。结果 IR组与非IR组比较T水平更高,LH、SHBG与FSH更低,差异均有统计学意义(P<0.01);治疗后,IR组与非IR组比较BMI、FG评分及WHR高,差异均有统计学意义(P<0.01)。结论青春期PCOS非IR者与IR者生殖内分泌指标存在较大差异,为此需注重调节胰岛素状态。
Objective To study the difference of reproductive and endocrine in patients with adolescent polycystic ovary syndrome (PCOS) with insulin resistance and non-insulin resistance. Methods Eighty - six PCOS patients admitted to the hospital were enrolled in this study. According to the degree of insulin resistance (IR), IR group (46 cases) and non - IR group (40 cases) were enrolled in the study. Two groups of reproductive endocrine parameters including FSH (LH), T (testosterone), and SHBG (sex hormone binding protein) were measured. The levels of these indexes were compared between the two groups and the FG score (hairiness score), BMI (body mass index) and WHR ratio). Results Compared with non-IR group, T level was higher in IR group and lower in LH, SHBG and FSH (P <0.01). After treatment, BMI, FG score and WHR were higher in IR group and non-IR group , The differences were statistically significant (P <0.01). Conclusion There is a big difference in reproductive and endocrine indexes between adolescent PCOS non-IR and IR, so we must pay attention to regulate insulin status.