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氯沙坦是一种治疗高血压的高选择性AT；非肽类口服有效的血管紧张素Ⅱ（AⅡ）受体阻滞剂。由于AⅡ还可以增加心衰病人的左室后负荷和前负荷，因此阻滞AT；受体就可改善心衰病人的血液动力学和临床症状。氯沙坦治疗充血性心衰的作用尚在研究之中。心衰并伴有肝、肾等各器官血流?
Losartan is a highly selective AT for the treatment of hypertension; a non-peptide orally available angiotensin II (AII) receptor blocker. As AII can also increase the left ventricular afterload in patients with heart failure and preload, thus blocking AT; receptor can improve hemodynamic and clinical symptoms in patients with heart failure. Losartan treatment of congestive heart failure is still under study. Heart failure and liver, kidney and other organs associated with blood flow?