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目的:了解湖北省围产儿出生缺陷发生情况及影响因素。方法:连续监测2001~2013年全省出生缺陷监测医院出生的妊娠满28周以上的死胎、死产和活产儿中出生缺陷的发生情况。结果:2001年全省围产儿出生缺陷发生率为81.07/万,2013年为135.25/万,围产儿出生缺陷发生率明显上升。城乡出生缺陷发生率比较无统计学差异(χ2=34.77,P>0.05),男性明显高于女性(χ2=66.05,P<0.001)。围产儿出生缺陷的主要类型有所变化,主要为先天性心脏病、多指(趾)、唇裂、外耳畸形、肢体短缩。结论:大力开展围产儿出生缺陷监测与干预工作,全面落实三级预防措施,能全面提高出生人口质量,有效降低围产儿出生缺陷发生率。
Objective: To understand the occurrence and influencing factors of birth defects in perinatals in Hubei province. Methods: The incidence of birth defects in stillbirths, stillbirths and live births born more than 28 weeks after birth in the birth defect monitoring hospitals in the province from 2001 to 2013 were continuously monitored. Results: The incidence of perinatal birth defects was 81.07 / million in the whole province in 2001 and 135.25 / million in 2013. The incidence of birth defects in perinatal children increased significantly. There was no significant difference in the incidence of birth defects between urban and rural areas (χ2 = 34.77, P> 0.05). The male was significantly higher than the female (χ2 = 66.05, P <0.001). The main types of perinatal birth defects vary, mainly congenital heart disease, multiple fingers (toes), cleft lip, outer ear deformity, limb shortening. CONCLUSION: Vigorously carry out the monitoring and intervention of birth defects in perinatal children and fully implement the three levels of prevention measures, which can comprehensively improve the quality of the birth population and effectively reduce the incidence of perinatal birth defects.