目的　观察WHO全球哮喘防治策略 (GINA)方案对 2 6 8例小儿哮喘的治疗效果。方法　对2 6 8例哮喘患儿持续吸入丙酸氟替卡松、间断吸入沙丁胺醇及长期服用抗炎症介质孟鲁司特钠 (顺尔宁 )治疗 ,峰流速仪及肺功能仪监测 ,避免触发因素 ,家庭教育管理等综合疗法跟踪观察 6～ 18个月。结果　总临床控制率为 5 6 % ,显效率 2 2 % ,有效率 16 % ,无效率 6 % ,总有效率为 94 % ;有 90 %的患儿治疗 6个月后最大呼气流速 (PEFR)值大于 90 % ;治疗期间未发现明显的不良反应。结论　GINA方案临床疗效满意。 Objective To observe the therapeutic effect of WHO Global Strategy for Asthma Control (GINA) on 268 pediatric asthma. Methods A total of 268 children with asthma were treated with continuous inhalation of fluticasone propionate, intermittent inhalation of albuterol and long-term administration of montelukast sodium (sirolimus), an anti-inflammatory mediator. Peak-flow velocity and pulmonary function tests were performed to avoid triggering factors. Education and other comprehensive follow-up monitoring 6 to 18 months. Results The total clinical control rate was 56%, the effective rate was 22%, the effective rate was 16%, the inefficiency rate was 6%, the total effective rate was 94%; 90% of the children treated for 6 months after the maximum expiratory flow rate (PEFR ) Value greater than 90%; no significant adverse reactions were found during the treatment. Conclusion The clinical efficacy of GINA is satisfactory.