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目的分析新兵风疹疫情,为部队新兵风疹疫情的预防控制工作提供一定依据。方法采用酶联免疫吸附试验检测健康新兵、风疹病人血清IgG、IgM抗体,PCR检测风疹病人血清病毒核酸。结果风疹发病初期病人血清风疹IgM吸光度值(A)(2.190±1.260)明显高于正常对照组(0.130±0.061,P<0.01)。风疹病人组恢复期血清风疹IgG检出阳性率(100.0%)、IgG吸光度值(A)(1.840±0.480)高于正常对照组(62.8%和0.870±0.600),差异有显著性(P<0.01);风疹IgG水平比发病初期升高4倍者占100.0%。10份病人血清PCR结果均为阳性。风疹疫苗免疫接种后阳转率为100.0%。结论在新兵中做好风疹的预防十分重要,早期发现病人并进行疫苗接种可有效控制疫情发展。
Objective To analyze the epidemic situation of recruit rubella, and provide some evidences for prevention and control of recruit rubella. Methods Serum IgG and IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA) in rubella and rubella patients. Serum viral nucleic acids were detected by PCR in rubella patients. Results The serum rubella IgM absorbance (A) (2.190 ± 1.260) in the early stage of rubella was significantly higher than that in the normal control group (0.130 ± 0.061, P <0.01). The positive rate of serum rubella IgG (100.0%) and IgG absorbance (A) (1.840 ± 0.480) were significantly higher in the rubella patients than in the normal controls (62.8% and 0.870 ± 0.600, P <0.01) ); Rubella IgG levels increased by 4 times than the early onset accounted for 100.0%. Serum PCR results of 10 patients were positive. Rubella vaccination positive rate of 100.0% after immunization. Conclusion It is very important to prevent rubella in recruits. Early detection of patients and vaccination can effectively control the epidemic.