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收集２４９例临床诊断或怀疑为尖锐湿疣的活检标本作病理形态学观察，组织学诊断为尖锐湿疣１４８例，可疑１８例，炎性增生８３例。抽取其中３０例尖锐湿疣、１０例可疑尖锐湿疣、１５例炎性增生作地高辛标记的ＨＰＶ６Ｂ／１１ＤＮＡ原位杂交。结果：尖锐湿疣组均阳性，可疑组１例阳性，炎性增生组均阴性。本文对尖锐湿疣的病理诊断及鉴别诊断进行了讨论。本组材料中的９２．８％的病例在组织学上得到了确诊，并且和ＨＰＶ６Ｂ／１１原位杂交结果相符，仅７．２％病例组织学列为可疑，需进一步作ＨＰＶ检测。
A total of 249 biopsy specimens with condyloma acuminatum were collected for histopathological examination. 148 cases of condyloma acuminatum, 18 cases of suspicious and 83 cases of inflammatory hyperplasia were collected. Thirty cases of condyloma acuminatum, 10 cases of suspected condyloma acuminata and 15 cases of inflammatory hyperplasia labeled with digoxigenin were selected for HPV6B / 11DNA in situ hybridization. Results: Condyloma acuminatum group was positive, 1 case of suspicious group, negative group of inflammatory hyperplasia. This article discusses the pathological diagnosis and differential diagnosis of genital warts. 92.8% of the cases in this group of materials were histologically confirmed, and in line with the results of in situ hybridization HPV6B / 11, only 7.2% of cases histological as suspicious, further testing for HPV.