整合素是一类重要的细胞表面分子,参与细胞增殖、分化、黏附和迁移等过程,在多种病理过程中发挥重要作用。近年来,关于整合素调控研究的不断深入及在肿瘤、组织纤维化和伤口愈合等治疗中发挥的重要作用不断被挖掘,整合素逐渐成为疾病诊断和治疗的新靶点。本文将对整合素的基因表达调控进行综述。 Integrins are a class of important cell surface molecules involved in cell proliferation, differentiation, adhesion and migration processes, play an important role in a variety of pathological processes. In recent years, the research on integrin regulation continues to deepen and its important role in the treatment of tumors, tissue fibrosis and wound healing has been continuously explored. Integrin has gradually become a new target of disease diagnosis and treatment. This article reviews the regulation of integrin gene expression.