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目的探讨进展期大肠癌患者围手术期的凝血功能状态变化相关的临床意义。方法采用分组对照方法检测10例良性手术和10例进展期大肠癌患者手术治疗前后DD含量。结果围手术期血浆DD水平呈动态变化。手术后,2组DD含量比手术前均明显上升,良性手术组于1周左右恢复,大肠癌手术组未恢复(P<0.05)。结论动态监测血浆DD水平,寻找有效手段控制凝血功能异常,对术后肿瘤复发有一定的预测和控制作用。
Objective To investigate the clinical significance of perioperative coagulation status in patients with advanced colorectal cancer. Methods The group control method was used to detect DD content before and after operation in 10 cases of benign surgery and 10 cases of advanced colorectal cancer. Results Perioperative plasma DD levels showed dynamic changes. After operation, the content of DD in two groups increased significantly compared with that before operation. The benign operation group recovered in about one week, and the colorectal cancer operation group did not recover (P <0.05). Conclusion The dynamic monitoring of plasma DD levels, looking for effective means to control coagulation dysfunction, postoperative tumor recurrence has some predictive and control.