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25-羟基维生素D是一种有神经活性的类固醇激素,主要作用是预防骨质疏松和调节钙代谢,其缺乏与自身免疫性疾病、糖尿病、恶性肿瘤及心血管疾病有密切关系。近年随研究深入,25-羟基维生素D水平与脑部疾病关系的研究越来越受到关注,尤其是其与缺血性卒中的相关性。本文就25-羟基维生素D与缺血性卒中相关性的研究进展作一综述。
25-Hydroxyvitamin D is a neuro-active steroid hormone that plays a major role in preventing osteoporosis and regulating calcium metabolism. Its lack is closely linked to autoimmune diseases, diabetes, malignancies and cardiovascular diseases. With the deepening of research in recent years, more and more attention has been paid to the relationship between the level of 25-hydroxyvitamin D and brain diseases, especially its relationship with ischemic stroke. This article reviews the research progress of the relationship between 25-hydroxyvitamin D and ischemic stroke.