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1例47岁女性患者因盆腔炎给予氨曲南1.0 g入0.9%氯化钠注射液250 ml静脉滴注2次/d,替硝唑0.4 g静脉滴注2次/d,保妇康栓1粒/d(阴道给药)。用药第4天患者出现乏力,实验室检查示肌酸激酶(CK)764 U/L,乳酸脱氢酶(LDH)357 U/L,α-羟丁酸脱酸酶(α-HBDH)293 U/L。次日停用氨曲南,其他药物未变。停用氨曲南第5天乏力缓解,CK 257 U/L,LDH 351 U/L,α-HBDH 162 U/L;第9天乏力消失,CK 166 U/L,LDH 331 U/L,α-HBDH 156 U/L,均在正常范围内。
A 47-year-old woman with pelvic inflammatory disease was given aztreonam 1.0 g 0.9% sodium chloride injection 250 ml intravenously 2 times / d, tinidazole 0.4 g intravenously 2 times / d, Baofukang suppository 1 capsule / d (vaginal administration). On the fourth day after treatment, the patient developed fatigue. The laboratory tests showed 764 U / L creatine kinase (CK), 357 U / L lactate dehydrogenase (LDH) and 293 U alpha-hydroxybutyric acid dehydrogenase / L. Aztreonam disabled the next day, other drugs have not changed. Withdrawal of aztreonam 5 days of fatigue, CK 257 U / L, LDH 351 U / L, α-HBDH 162 U / L; disappeared on the 9th day, CK 166 U / L, LDH 331 U / L, α -HBDH 156 U / L, all within the normal range.