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目的观察激素联合中药制剂治疗儿童肾病综合征的临床效果。方法将45例患儿随机分为对照组和治疗组,对照组22例,采用单纯激素治疗,治疗组23例,采用健脾固肾汤联合激素进行治疗,并针对患儿的近期及远期疗效进行,随访3年以上。结果近期疗效中对照组的总有效率为63.6%,治疗组为95.7%,治疗组明显优于对照组(P<0.05);远期疗效中对照组的总有效率为66.7%,治疗组为95.0%,治疗组亦明显优于对照组(P<0.01)。结论采用中西医结合治疗儿童肾病综合征效果明显,能减轻不良反应,安全有效,值得推广。
Objective To observe the clinical effect of hormone combined with traditional Chinese medicine in the treatment of children with nephrotic syndrome. Methods Forty-five children were randomly divided into control group and treatment group. The control group consisted of 22 patients. Hormone therapy alone was used in the treatment group. 23 cases were treated with Jianpi Gushen Decoction combined with hormones, Efficacy, follow-up more than 3 years. Results The total effective rate of the control group was 63.6% in the short term, 95.7% in the treatment group, which was significantly better in the treatment group than in the control group (P <0.05). The total effective rate in the long-term efficacy group was 66.7% 95.0%, the treatment group was also significantly better than the control group (P <0.01). Conclusion The treatment of children with nephrotic syndrome with traditional Chinese and western medicine has obvious effect, can reduce adverse reactions, is safe and effective, and is worth promoting.