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有人指出纸烟雾中的氧化剂能够使α_1-抗胰旦白酶抑制弹性旦白酶的功能失去活性。在试管内或作吸烟者的肺灌洗液的实验,已经得到证实。在这些研究中,我们测定出纸烟雾冷凝到氧化邻联(二)茴香胺的标准能力与它灭活α_1-抗胰旦白酶抑制弹性旦白酶的活性密切相关。在以后的研究中均用此两种测定法。
It was pointed out that the oxidant in the paper smoke could inactivate the function of α 1 -anti-trypsin inhibition of elastase. Experiments in vitro or in lung lavage of smokers have been demonstrated. In these studies, we determined that the standard ability of the output fugitive to condense to oxidize vicinal anisidine is closely related to the activity of inactivated α1-antitamase to inhibit elastase. Both of these assays are used in later studies.