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目的观察消旋卡多曲治疗婴幼儿腹泻的临床疗效。方法 108例秋冬季腹泻病患儿随机分成观察组和对照组,应用利巴韦林,双八面体蒙脱石,微生物调节剂及液体疗法等综合治疗作为对照组,在此基础上加用抗分泌剂消旋卡多曲作为观察组。结果治疗3 d对照组和观察组总有效率分别为61.1%和92.6%,两组总有效率比较差异有统计学意义(P<0.01)。结论消旋卡多曲同时配合利巴韦林、肠黏膜保护剂、ORS、微生物调节剂等药物使用,对婴幼儿水样腹泻的治疗效果良好,使用方便安全,值得临床推广使用。
Objective To observe the clinical efficacy of racecadotril in the treatment of infantile diarrhea. Methods A total of 108 children with autumn and winter diarrhea were randomly divided into observation group and control group. Ribavirin, dual octahedral montmorillonite, microbiological regulator and liquid therapy were used as control group. On the basis of this, Secretion of racecadotril as the observation group. Results The total effective rates of the control group and the observation group were 61.1% and 92.6% after 3 days of treatment, respectively. The total effective rate was significantly different between the two groups (P <0.01). Conclusion Racecadotril combined with ribavirin, intestinal mucosal protective agent, ORS, microbial agents and other drugs used in infants and children with water-based diarrhea treatment effect is good, easy to use and safe, worthy of clinical promotion and use.