论文部分内容阅读
众所周知,目前大肠癌的治疗仍以手术治疗为唯一可靠的手段。然而单纯手术切除大肠癌患者的五年生存率也只有30％左右,Turnbull从五年生存率的分析中还注意到,术后二年内发生复发、转移死亡者为最多见,且常死于致命的肝转移。四年前Siknner等报告了先用手术切除明显的主瘤灶,再用异种特异的IRNA来消灭残余的瘤细胞,使3例晚期肾癌均取得良好疗效。因此为了提高术后大肠癌病人的生存率,减少术后的复发和转移。我们采用了
As we all know, the treatment of colorectal cancer is still the only reliable means of surgical treatment. However, the 5-year survival rate of patients with colorectal cancer after surgery alone is only about 30%. Turnbull also noted from the analysis of five-year survival rate that recurrence and metastasis death occurred most frequently within 2 years after surgery, and often died of fatalities. Liver metastasis. Four years ago, Siknner et al reported that they first surgically excised the obvious main tumor foci, and then used heterologous specific IRNAs to destroy the remaining tumor cells, so that 3 cases of advanced renal cell carcinoma achieved good results. Therefore, in order to improve the survival rate of patients with postoperative colorectal cancer, reduce postoperative recurrence and metastasis. We used