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目的:探讨间苯三酚在双气囊小肠镜检查中的临床效果和应用价值。方法:选择2007年6月至2008年9月在郑州大学二附院行双气囊小肠镜检查的36例患者,随机分为间苯三酚组和安慰剂对照组,每组各18例,比较2组患者腹痛情况、小肠镜完成时间和检查前、中、后的血压和心率变化等。结果:2组疼痛值差异无统计学意义。间苯三酚组检查完成时间明显短于对照组。各组检查前、中、后收缩压、舒张压及心率差异均无统计学意义。疼痛值和检查完成时间差异无统计学意义。结论:小肠镜检查前及检查中静脉注射间苯三酚,能够部分缓解小肠镜检查的疼痛,缩短检查时间,其作用安全有效,无明显不良反应,可广泛应用于临床。
Objective: To investigate the clinical effect and application value of phloroglucinol in double balloon enteroscopy. Methods: From June 2007 to September 2008, 36 patients with double balloon enteroscopy in Second Affiliated Hospital of Zhengzhou University were randomly divided into phloroglucinol group and placebo control group, with 18 cases in each group. 2 cases of patients with abdominal pain, the time to complete colonoscopy and examination before, during and after changes in blood pressure and heart rate. Results: There was no significant difference in pain value between the two groups. Phloroglucinol group examination completed time was significantly shorter than the control group. There was no significant difference in systolic blood pressure, diastolic blood pressure and heart rate before, during and after examination in each group. There was no significant difference in pain value and examination completion time. Conclusions: The phloroglucinol injection before and during enteroscopy can partially relieve the pain of the small bowel examination and shorten the examination time. Its effect is safe and effective without obvious adverse reactions and can be widely used in clinic.