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神经生长因子是一种影响神经细胞发育、存活的多能神经营养因子,其中枢和周围效直与神经细胞凋亡密切相关。本文对NGF与神经系统发育、神经损伤及疾病过程中所发生的细胞凋亡的关系以及NGF的抗凋亡作用等方面的研究状况进行了综述。
Nerve growth factor is a multipotent neurotrophic factor that affects the development and survival of nerve cells. Its central and peripheral potency are closely related to neuronal apoptosis. This review summarizes the relationship between NGF and the development of the nervous system, the neural damage and the apoptosis in the process of the disease and the anti-apoptotic effect of NGF.