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目的 :观察自制经鼻持续气道正压 (简易CPAP)治疗新生儿急性呼吸衰竭 (ARF)的疗效。方法 :50例使用简易CPAP ,用鼻塞、直径 1 .0cm的橡胶管、玻璃管连续氧源和水封瓶 ,根据原发病及血气分析结果调节氧流量及CPAP压力 ,检测治疗前后血气分析的变化。结果 :1 8例 (36.0 % )在 1～ 5min内发绀缓解 ,1 3例 (2 6.0 % )及 7例 (1 4 .0 % )分别在 0 .5 ,2h内发绀缓解。总有效率 76 .0 %。 32例治疗前后动脉血气变化氧分压和pH值差异有显著性 (P <0 .0 5 ,P <0 .0 1 ) ,二氧化碳分压差异无显著性 (P >0 .0 5)。结论 :简易CPAP是治疗新生儿ARF有效方法 ,取材经济 ,方法简单
Objective: To observe the curative effect of home-made nasal continuous positive airway pressure (CPAP) on neonatal acute respiratory failure (ARF). Methods: Fifty patients underwent simple CPAP with nasal prongs, rubber tubes with a diameter of 1.0 cm, continuous glass tube oxygen source and water-sealed bottles. The oxygen flow rate and CPAP pressure were adjusted according to the primary disease and blood gas analysis results. Blood gas analysis Variety. RESULTS: Eighteen patients (36.0%) regained cyanosis within 1 ~ 5 min, and 13 patients (2 6.0%) and 7 patients (14.0%) regained cyanosis within 0.5 and 2 h, respectively. The total efficiency of 76 .0%. There were significant differences in arterial blood gas oxygen partial pressure and pH between before and after treatment (P <0.05, P <0.01) and no significant differences in partial pressure of carbon dioxide (P> 0.05). Conclusions: Simple CPAP is an effective method for the treatment of ARF in newborns, which is economical and simple