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目的探讨阿莫西林和阿莫西林-克拉维酸钾的不良反应。方法收集100例感染患者,随机均分为观察组和对照组。对照组使用阿莫西林治疗,观察组使用阿莫西林-克拉维酸钾治疗,比较不良反应。结果两组患者均出现胃肠、循环、中枢神经系统以及皮肤系统的不良反应,但观察组不良反应发生率明显低于对照组患者,差异为显著性差异(P<0.05),有统计学意义。结论阿莫西林-克拉维酸钾在对感染患者治疗过程中安全性更佳,相比阿莫西林值得推广应用。
Objective To investigate the adverse reactions of amoxicillin and amoxicillin-potassium clavulanate. Methods 100 cases of infected patients were randomly divided into observation group and control group. The control group was treated with amoxicillin, the observation group was treated with amoxicillin-clavulanate potassium, and the adverse reactions were compared. Results The gastrointestinal, circulatory, central nervous system and skin system adverse reactions occurred in both groups, but the incidence of adverse reactions in the observation group was significantly lower than that in the control group (P <0.05), with statistical significance . Conclusions Amoxicillin-clavulanate potassium is more safe in the treatment of infected patients, which is worthy of promotion and application compared with amoxicillin.