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目的探讨中晚期宫颈癌运用不同放疗方案治疗的临床效果。方法选择2010年1月至2011年1月中晚期宫颈癌患者68例为研究对象,按照数字随机表法分为两组,对照组给予单纯放疗治疗,观察组运用同步放化疗治疗,比较分析两组的治疗效果。结果观察组临床缓解率高于对照组(P<0.05);治疗期间,观察组不良反应发生率高于对照组,但组间比较差异未见统计学意义(P>0.05)。随访3~5年,观察组转移率和复发率均低于对照组,生存率高于对照组,组间比较差异有统计学意义(P<0.05);两组治疗时间比较差异有统计学意义(P<0.05)。结论相比较单纯放疗而言,同步放化疗治疗中晚期宫颈癌,虽然增加了发生不良反应的风险,但其临床缓解率较高,能够提高患者的生存率,值得推广。
Objective To investigate the clinical effect of different radiotherapy regimens in the treatment of advanced cervical cancer. Methods Sixty-eight patients with advanced cervical cancer from January 2010 to January 2011 were selected as the study subjects. The patients were divided into two groups according to the digital random table method. The control group received radiotherapy alone and the observation group received concurrent chemoradiotherapy. Group treatment effect. Results The clinical remission rate in the observation group was higher than that in the control group (P <0.05). During the treatment period, the incidence of adverse reactions in the observation group was higher than that in the control group, but there was no significant difference between the two groups (P> 0.05). The follow-up of 3 to 5 years, the observation group metastasis rate and recurrence rate were lower than the control group, the survival rate was higher than the control group, the difference between the two groups was statistically significant (P <0.05); the two groups were statistically significant differences in treatment time (P <0.05). Conclusion Compared with radiotherapy alone, concurrent chemoradiotherapy for advanced cervical cancer, although increasing the risk of adverse reactions, but its higher clinical remission rate, can improve the survival rate of patients, it is worth promoting.