论文部分内容阅读
目的观察评估曲美他嗪治疗冠心病心功能不全的临床疗效。方法88例冠心病心功能不全患者随机分为治疗组和对照组,治疗组48例给予常规治疗基础上加用曲美他嗪60mg/d,对照组40例给予常规治疗:利尿剂,ACEI、β阻滞剂、洋地黄类等药物治疗,两组共治疗8周,观察治疗前后两组病人的左室射血分数(LVEF),6分钟步行距离改善情况。结果治疗组总有效率达88%,对照组总有效率为65%,治疗前后两组相比LVEF,6min步行距离均有显著改善(p<0.01),治疗组疗效优于对照组。结论曲美他嗪治疗冠心病心功能不全可提高疗效。
Objective To evaluate the clinical efficacy of trimetazidine in the treatment of heart failure with coronary heart disease. Methods 88 patients with CHD were randomly divided into treatment group and control group. 48 patients in the treatment group were treated with trimetazidine 60 mg / d on the basis of routine treatment and 40 patients in the control group were given routine treatment: diuretics, ACEI, β blockers, digitalis and other drugs, the two groups were treated for 8 weeks, before and after treatment in both groups observed left ventricular ejection fraction (LVEF), 6-minute walking distance to improve the situation. Results The total effective rate was 88% in the treatment group and 65% in the control group. Before and after treatment, LVEF and 6-minute walk distance were significantly improved (p <0.01). The curative effect of the treatment group was better than that of the control group. Conclusion Trimetazidine treatment of coronary heart disease can improve heart failure.