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目的:涎腺淋巴上皮癌是一种罕见的恶性肿瘤,本文主要探讨涎腺淋巴上皮癌的发病情况、病理特点及其诊治措施。方法:回顾性分析2006-2012年间于南方医科大学南方医院就诊的17例涎腺淋巴上皮癌患者,分析其临床特点与治疗方法对预后的影响。结果:17例中,男10例,女7例;Ⅱ、Ⅲ、Ⅳ期患者分别为7(41.2%)、4(23.5%)、6(35.3%)例。术后平均随访时间为2.56年,随访12例患者情况稳定;5例患者分别在术后3年内出现局部复发和(或)远处转移,其中4例已死亡。结论:涎腺淋巴上皮癌是头颈部恶性程度较高的肿瘤之一,好发于腮腺及下颌下腺。治疗应行原发灶扩大切除及根治性颈淋巴清扫术,并结合放化疗以提高疗效。
Objective: Salivary gland lymphoepithelial carcinoma is a rare malignant tumor, this article mainly discusses the incidence of salivary gland lymphoepithelial carcinoma, pathological features and diagnosis and treatment measures. Methods: A retrospective analysis of 17 cases of salivary gland lymphoepithelial carcinoma treated in Nanfang Hospital of Southern Medical University from 2006 to 2012 was conducted to analyze the clinical characteristics and the influence of treatment on the prognosis. Results: Seventeen (41.2%), four (23.5%) and six (35.3%) patients were found in 17 cases, including 10 males and 7 females. The average follow-up time was 2.56 years. The follow-up of 12 patients was stable. Five patients had local recurrence and / or distant metastasis within 3 years after operation, and 4 of them died. Conclusion: Lymphoepithelial carcinoma of the salivary gland is one of the most malignant tumors of the head and neck. It occurs predominantly in the parotid and submandibular glands. Treatment should be the primary tumor expansion and removal of radical neck dissection, combined with radiotherapy and chemotherapy to improve the curative effect.