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目的分析血清降钙素原在败血症早期诊断中的临床应用价值。方法选取东莞市厚街医院2012年1月至2014年10月收治的40例败血症患者作为观察组,同时选取20例非败血症患者作为对照组,分别取两组患者外周血清样本,检测血清降钙素原浓度,分析其在败血症早期诊断中的应用价值。结果败血症患者血清降钙素原(PCT)浓度均高于2.0 ng/ml,其中2.1~5.0 ng/ml者30例,5.1~10.0 ng/ml者8例,>10.0 ng/ml者2例,败血症患者血清PCT浓度水平明显高于对照组(P<0.05);本研究60例患者中血培养阳性组38例,阴性22例,阳性组血清PCT浓度水平均>2.0 ng/ml,其整体血清浓度水平明显高于血培养阴性组(P<0.05)。结论在败血症患者的早期诊断中,采取血清降钙素原检测方案兼具较高的敏感度与特异性,可为患者的早期治疗提供指导,值得推广。
Objective To analyze the clinical value of serum procalcitonin in the early diagnosis of sepsis. Methods Forty septicemic patients admitted to Houjie Hospital of Dongguan City from January 2012 to October 2014 were selected as the observation group. Twenty non-sepsis patients were selected as the control group. Peripheral serum samples were taken from two groups to detect the levels of serum calcitonin Elemental concentration, analysis of its value in the early diagnosis of sepsis. Results Serum procalcitonin (PCT) concentrations were all higher than 2.0 ng / ml in sepsis patients, of which 30 cases were 2.1 ~ 5.0 ng / ml, 8 cases were 5.1 ~ 10.0 ng / ml and 2 cases were> 10.0 ng / Serum PCT concentration in patients with sepsis was significantly higher than that in the control group (P <0.05). In the 60 patients, 38 patients were positive for blood culture and 22 patients were negative. The serum concentrations of PCT in the positive group were> 2.0 ng / ml, The concentration level was significantly higher than that of blood culture negative group (P <0.05). Conclusion In the early diagnosis of sepsis patients, the serum procalcitonin detection program combined with high sensitivity and specificity can guide the early treatment of patients, which is worth promoting.