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16名身体健康男性青年为受试对象.用脑血流图(REG)评价间断缺氧适应后再暴露5000m急性缺氧时的脑血流(CBF)改变.结果表明,适应组急性高山反应的发生率低,发病程度较轻.分析REG的主峰波幅,流入容积速度、重搏波深度、上升角和顶峰角等参数显示,急性缺氧时适应组CBF减少,对照组CBF增加.高山反应轻度者CBF减少;中度者CBF改变不明显;重度者CBF增多.这提示:(1)急性高山病的发生可能与CBF的改变有关.(2)间断减压缺氧适应可以改善脑循环和减轻高山反应症状.
Sixteen healthy male volunteers were enrolled in this study.The changes of cerebral blood flow (CBF) at acute hypoxia of 5000m after intermittent hypoxia adaptation were evaluated by cerebral blood flow diagram (REG) .The results showed that the adaptive alpine response Low incidence and mild disease.The analysis of the main peak amplitude, inflow volume velocity, Doppler wave depth, ascending angle and peak angle showed that the CBF of the adaptive group decreased and the CBF increased in the control group The degree of CBF decreased; moderate CBF change was not obvious; severe CBF increased.This suggests that: (1) the occurrence of acute mountain sickness may be related to changes in CBF (2) Intermittent decompression and hypoxia can improve cerebral circulation and Alleviate the symptoms of alpine reactions.