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结扎沙土鼠双侧颈总动脉,继之重灌流。结果表明,荞麦花粉对45min脑缺血后重灌流6h的卒中指数及24h的死亡率均有明显抑制作用。其机制可能与抗氧化作用有关。异紫堇定对脑缺血重灌流损伤无保护作用。
The common carotid artery was bilaterally ligated to the gerbil followed by re-perfusion. The results showed that the buckwheat pollen inhibited the stroke index and 24-hour mortality rate after reinfusion 6h after 45 min cerebral ischemia. Its mechanism may be related to the antioxidant effect. Isopurinidine has no protective effect on cerebral ischemia reperfused injury.