论文部分内容阅读
目的 :观察静脉应用胺碘酮对心衰合并快速房颤的疗效。方法 :心衰患者 5 2例随机分为两个治疗组。胺碘酮组给胺碘酮 15 0mg生理盐水稀释后缓慢注射 ,然后以 0 5mg/min维持静滴 ,2 4小时总量不超过 80 0mg。西地兰组 :先用西地兰 0 2mg稀释后缓慢静推 ,若 2 0分钟无效再给 0 2mg ,2 4小时总量不超过 1 0mg ,两组常规治疗相同。比较首次用药后不同时刻的心室率变化、2 4小时后复律情况。结果 :两组用药后心室率均明显下降 ,西地兰组起效快于胺碘酮组 (P <0 0 1) ,胺碘酮组有效率高于西地兰组 (P <0 0 5 ) ,胺碘酮组用药后转复窦律 13例 ,西地兰组 5例 (P <0 0 5 )。结论 :胺碘酮可有效降低心衰合并快速房颤患者的心室率 ,并能使部分患者房颤转复
Objective: To observe the effect of intravenous amiodarone on heart failure complicated with rapid atrial fibrillation. Methods: Fifty-two patients with heart failure were randomly divided into two treatment groups. Amiodarone group to amiodarone 150mg normal saline diluted injection slowly, then 0 5mg / min to maintain intravenous infusion, 24 hours total amount of not more than 80 0mg. Cedilanid group: first with cedilanid 2mg diluted slow intravenous push, if 20 minutes invalid given 0 2mg, 2 4 hours total does not exceed 1 0mg, the two groups of conventional treatment the same. Ventricular rate changes at different times after the first administration were compared, and the situation of cardioversion after 24 hours was compared. Results: The ventricular rate was significantly decreased in both groups, and the activity in cedilanid group was faster than that in amiodarone group (P <0.01). The amiodarone group was more effective than cedilanid (P <0.05). ), Amiodarone group after treatment of sinus rhythm in 13 cases, 5 cases of cedilanid (P <0 05). Conclusion: Amiodarone can effectively reduce the ventricular rate in patients with CHF due to heart failure, and can make some patients atrial fibrillation