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目的探讨肝细胞肝癌切除后复发的预后相关因素及合理治疗方法。方法1983年1月至1997年1月271例肝癌切除后有134例复发,对其一般情况、肿瘤特性及外科措施进行多因素分析,同时比较复发后不同治疗方法的结果。结果复发时间在术后1年内、首次手术时AFP>1000μg/L、肿瘤直径>5cm、门静脉有癌栓、外科切缘为0及术前未行肝动脉插管化疗者等6大因素直接影响复发者的预后,同时发现,复发肿瘤可行再次切除或行肝移植治疗。结论肿瘤特性和外科治疗是直接影响肝癌复发后预后的两大因素,复发后再次肝切除或肝移植可获好的疗效。
Objective To explore the prognostic factors related to recurrence after hepatectomy for hepatocellular carcinoma and its rational treatment. Methods From January 1983 to January 1997, 271 cases of recurrence of 271 cases of hepatocellular carcinoma relapsed. Their general conditions, tumor characteristics and surgical measures were analyzed by multivariate analysis. The results of different treatment methods after relapse were compared. Results The recurrence time was directly affected by six factors such as AFP>1000μg/L, tumor diameter>5cm, portal vein tumor thrombosis, surgical margin of 0, and no preoperative hepatic artery catheterization chemotherapy within 1 year after operation. The prognosis of relapsers also found that recurrent tumors may be resected or treated with liver transplantation. Conclusion The tumor characteristics and surgical treatment are two major factors that directly affect the prognosis of liver cancer after recurrence. After recurrence, recurrent liver resection or liver transplantation can obtain good curative effect.