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目的研究胃肠道间质瘤的临床特点、辅助检查及预后。方法对2002-2010年在吉林市第二中心医院经病理诊断的所有胃肠道间质瘤患者进行回顾性分析。结果 51例中胃、小肠和结直肠分别为49.0%、39.2%、11.8%。70%患者有临床症状,对于复发或转移的患者,伊马替尼治疗有统计学意义。结论胃肠道间质瘤不同于其他消化道肿瘤,辅助检查中超声内镜、CT检查意义重大。肿瘤原发部位、大小、核分裂相和组织学类型是评估其预后及危险性的重要因素,服用格列卫是目前最有效的药物治疗方法。
Objective To study the clinical features, gastrointestinal stromal tumors, auxiliary examination and prognosis. Methods All patients with gastrointestinal stromal tumors diagnosed by pathology in the Second Central Hospital of Jilin City from 2002 to 2010 were retrospectively analyzed. Results The stomach, small intestine and colorectum were 49.0%, 39.2% and 11.8% respectively in 51 cases. Seventy percent of patients had clinical symptoms and imatinib treatment was statistically significant for patients with relapsed or metastatic disease. Conclusion Gastrointestinal stromal tumor is different from other gastrointestinal tumors, ultrasound examination in the endoscopic ultrasound, CT examination of great significance. The primary tumor location, size, mitotic phase and histological type are important factors to evaluate the prognosis and risk. Taking Gleevec is the most effective drug treatment.