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目的观察孟鲁司特、酮替芬、丙卡特罗联合治疗特应性体质儿童慢性咳嗽的临床疗效。方法将358例特应性体质慢性咳嗽的门诊患儿随机分成治疗组和对照组。治疗组给予孟鲁司特、酮替芬、丙卡特罗联合口服,同时予以止咳化痰等对症治疗;对照组给予开瑞坦抗过敏和止咳化痰对症治疗。结果治疗组临床疗效明显优于对照组(P<0.001)。结论孟鲁司特、酮替芬、丙卡特罗联合治疗特应性体质儿童慢性咳嗽,疗效显著,安全性好。
Objective To observe the clinical efficacy of montelukast, ketotifen and procaterol in the treatment of chronic cough in children with atopic constitution. Methods 358 cases of atopic outpatients with atopic chronic cough were randomly divided into treatment group and control group. The treatment group was given montelukast, ketotifen, procaterol orally, while symptomatic treatment of cough and phlegm; the control group was given Katrine anti-allergy and cough and phlegm symptomatic treatment. Results The clinical efficacy of the treatment group was significantly better than that of the control group (P <0.001). Conclusions Montelukast, ketotifen and procaterol are effective in treating chronic cough in children with atopic constitution. The curative effect is obvious and the safety is good.