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目的探讨超声引导下聚桂醇硬化治疗在出血性结节性甲状腺肿的应用价值。方法超声引导下对63例经病理证实为出血性结节性甲状腺肿的患者进行囊液抽吸,按囊液容积1/3~1/2的比例注入聚桂醇并留置。治疗过程中观察并记录患者的反应,并于术后1、6、12、24个月观察结节体积变化情况。结果治疗前所有病灶均为囊性成分>90%的结节,最大体积15.6ml,平均体积为(10.1±2.3)ml,治疗后第24个月随访,最大体积4.9ml,平均体积为(1.0±0.3)ml,治疗总有效率96.8%,治愈率为88.9%,2年内治愈率随时间延长而上升。治疗过程无疼痛、醉酒样等不良反应,仅1例感轻微胸闷。结论超声引导下聚桂醇硬化治疗出血性结节性甲状腺肿是一种疗效肯定、安全可靠的治疗方法。
Objective To investigate the value of ultrasound-guided lauryl alcohol sclerosis in hemorrhagic nodular goiter. Methods Sixty-three patients with pathologically confirmed hemorrhagic nodular goitre were enrolled in this study under the guidance of ultrasound. After injection of lauromacyl alcohol in the ratio of 1/3 to 1/2 of the volume of cystic fluid, they were placed indwelling. During the course of treatment, the patient’s reaction was observed and recorded. The changes of nodule volume were observed at 1, 6, 12 and 24 months after operation. Results All lesions were cystic> 90% of nodules before treatment. The maximum volume was 15.6ml and the average volume was (10.1 ± 2.3) ml. After 24 months of treatment, the maximum volume was 4.9ml and the average volume was (1.0 ± 0.3) ml, the total effective rate was 96.8% and the cure rate was 88.9%. The cure rate increased with the passage of time within two years. No pain during treatment, drunk and other adverse reactions, only 1 case of mild chest tightness. Conclusion Ultrasound-guided lauryl alcohol sclerosis treatment of hemorrhagic nodular goiter is a sure effect, safe and reliable treatment.