主要是由a-地中海贫血和纯合性β-地中海贫血结合形成的不同的遗传相互作用可能产生中间型地中海贫血。其临床后果实际上是不能预测的。在产前诊断时这种相关的证据引起一些遗传咨询问题,而且要求进行有关的血液学研究。本文报导一例妊娠21周的孕妇,到作者的研究中心进行产前诊断,血液学资料符合 Different genetic interactions, mainly formed by the combination of a-thalassemia and homozygous β-thalassemia, may produce intermediate thalassemia. The clinical consequences are virtually unpredictable. This associated evidence in prenatal diagnosis raises some genetic counseling questions and calls for relevant hematological studies. This article reports a pregnant woman of 21 weeks of pregnancy, to the author’s research center for prenatal diagnosis, hematology data consistent