目的　探讨超声检测颈动脉粥样硬化斑块应变及应变率的可行性 ,颈动脉粥样硬化斑块应变及应变率的分布情况。方法　选取 2 6例冠心病患者的 3 5处颈动脉斑块 ,运用组织速度成像 (TVI)和Q analysis软件测量斑块不同部位的位移、斑块应变及应变率的峰值 ,对同一处斑块分别在不同参数条件下测量斑块应变及应变率峰值。结果　斑块应变和应变率测量值在不同参数条件下差异无显著性意义 ;不同部位的斑块应变、应变率差异具有显著性意义 ;急性心肌梗死、陈旧性心肌梗死和心绞痛 3组患者颈动脉斑块的受力情况存在差异。斑块肩部和纤维帽表面是应变最集中的部位 ,并且沿径向方向 ,从斑块表面至基底部 ,应变及应变率呈减小趋势。结论　TVI技术可以用于颈动脉斑块应变及应变率的分析。不同类型的斑块肩部及不同部位应变及应变率存在差异 Objective To investigate the feasibility of detecting the strain and strain rate of carotid atherosclerotic plaque by ultrasound and the distribution of strain and strain rate of carotid atherosclerotic plaque. Methods Twenty-five carotid plaques in 26 patients with coronary heart disease were selected. Tissue velocity imaging (TVI) and Q analysis software were used to measure the displacement, plaque strain and strain rate of different parts of the plaque. Plaque strain and strain rate peak were measured under different parameters respectively. Results There was no significant difference between the measured values ​​of strain and strain rate under different parameters. The differences of plaque strain and strain rate at different sites were significant. The incidence of carotid artery in AMI, AMI and angina group was significant There are differences in the force of plaque. Plaque shoulders and fiber cap surfaces are the areas where strain is most concentrated, and in the radial direction, from the plaque surface to the basal part, the strain and strain rates tend to decrease. Conclusion TVI technique can be used for the analysis of carotid plaque strain and strain rate. Different types of plaque shoulder and different parts of the strain and strain rate differences