论文部分内容阅读
目的:观察舒筋活络胶囊的镇痛作用和对免疫功能的影响。方法:采用热板法和扭体法考察其对小鼠疼痛的影响;用二硝基氯苯(DNCB)诱导的迟发型超敏反应(DTH)和溶血素测定观察对细胞免疫和体液免疫的影响。结果:舒筋活络胶囊1.66g.kg-1、0.83g.kg-1明显抑制醋酸所致的小鼠疼痛,延长潜伏期;在给药后45,60min能显著提高小鼠痛阈值;能显著抑制DNCB诱导的小鼠DTH反应;能显著抑制小鼠溶血素抗体生成。其1.66g.kg-1对小鼠胸腺生长有抑制作用。结论:舒筋活络胶囊有一定镇痛和抑制免疫功能的作用。
Objective: To observe the analgesic effect of Shujin Huoluo capsule and its effect on immune function. METHODS: The effect of pain on mice was investigated by hot plate method and writhing method; and the effects of DHL and hemolysin induced by dinitrochlorobenzene (DNCB) on cellular immunity and humoral immunity were observed. influences. Results: Shujinhuoluo capsules 1.66g.kg-1, 0.83g.kg-1 significantly inhibited the pain caused by acetic acid in mice and prolonged the incubation period; at 45 and 60 minutes after administration, the pain threshold of mice was significantly increased; DNCB-induced mouse DTH response; can significantly inhibit mouse hemolysin antibody production. Its 1.66 g.kg-1 inhibited thymus growth in mice. Conclusion: Shujinhuoluo capsule has certain analgesic and anti-immune functions.