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目的:观察胰岛素泵对初诊2型糖尿病的疗效。方法:选取80例初诊2型糖尿病随机分为短期持续皮下注射胰岛素泵(CSII)组及皮下注射胰岛素(MSII)组。结果:提示CSII组及MSII组治疗均可有效降低血糖,但前者显著优于MSII组(P<0.01),两组均可改善初诊2型糖尿病患者胰岛β细胞功能,减轻胰岛素抵抗,CSII组较MSII组效果好(P<0.01)。结论:胰岛素泵可迅速有效使初诊2型糖尿病患者血糖达标,消除高血糖的毒性作用,缩短血糖达标天数,减少胰岛素用量,降低低血糖发生率,可延缓胰岛β细胞功能的衰退。
Objective: To observe the effect of insulin pump on newly diagnosed type 2 diabetes mellitus. Methods: Eighty newly diagnosed type 2 diabetic patients were randomly divided into short-term continuous subcutaneous insulin pump (CSII) group and subcutaneous insulin injection (MSII) group. Results: It is suggested that the treatment of CSII group and MSII group can effectively reduce the blood sugar, but the former is significantly better than the MSII group (P <0.01). Both groups can improve the pancreatic β-cell function and insulin resistance in newly diagnosed type 2 diabetic patients. MSII group effect (P <0.01). Conclusion: Insulin pump can quickly and effectively up-regulate the blood glucose of newly diagnosed type 2 diabetic patients, eliminate the toxic effect of hyperglycemia, shorten the number of days of blood glucose compliance, reduce the dosage of insulin, reduce the incidence of hypoglycemia and delay the decline of pancreatic β-cell function.