:目的　研究近十年来消化性溃疡合并出血的发病情况及变化趋势。方法　对我院 1988～ 1997年由胃镜检出的3 967例上消化道出血的病例资料进行分析。结果　共检出消化性溃疡合并出血 3 167例 ,占上消化道出血的 79.8%。其中十二指肠球部溃疡 2 3 2 8例 ,占 73 .5 %。胃溃疡 62 8例 ,占 19.8%。复合溃疡 2 11例 ,占 6.66% ,男女之比 3 .5∶1,好发于季节交替及寒冷季节。消化性溃疡合并出血在上消化道出血的比例 ,从 1988年的 83 .2 %渐降至 1997年的 65 .2 %。结论　消化性溃疡仍是上消化道出血的主要原因 ,但近十年来其所占比例呈下降趋势 Objective To study the incidence and trend of peptic ulcer bleeding in recent ten years. Methods The data of 3 967 cases of upper gastrointestinal bleeding detected by gastroscope from 1988 to 1997 in our hospital were analyzed. Results A total of 3 167 cases of peptic ulcer with hemorrhage were detected, accounting for 79.8% of upper gastrointestinal bleeding. Among them, duodenal ulcer 2 338 cases accounted for 73.5%. 628 cases of gastric ulcer, accounting for 19.8%. Complex ulcer 2 11 cases, accounting for 6.66%, the ratio of men and women 3 .5: 1, occur in the seasonal alternation and the cold season. Peptic ulcer bleeding in the upper gastrointestinal bleeding ratio, from 83.2% in 1988 decreased to 65.2% in 1997. Conclusions Peptic ulcer is still the main cause of upper gastrointestinal bleeding, but its proportion has been declining in the recent ten years