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背景动脉僵硬度是心血管疾病的独立危险因素。中心动脉反射波增强指数(AIx)是反映全身动脉僵硬度的重要指标,血压水平的变化与其有重要的关系。目的研究新疆哈萨克族和维吾尔族正常人群AIx,分析影响AIx的相关因素。方法选取新疆地区413例哈萨克族及587例维吾尔族正常人群。对研究对象进行问卷调查、一般体格检查及血糖、血脂、肾功能和C反应蛋白的检测,采用Sphygmocor脉搏波分析系统检测中心动脉收缩压(cSBP)及AIx。结果新疆哈萨克族正常人群AIx值高于新疆维吾尔族[(28.4±11.8)%比(23.3±11.5)%,P<0.05],相关性分析结果表明AIx与年龄呈正相关(哈萨克族:r=0.388,P<0.05;维吾尔族:r=0.386,P<0.05)。多元逐步回归分析示性别、年龄、cSBP、收缩压、舒张压是新疆哈萨克族AIx的影响因素,而性别、年龄、cSBP、收缩压、舒张压、C反应蛋白是新疆维吾尔族AIx的影响因素。结论新疆哈萨克族正常人群AIx值高于新疆维吾尔族,且与年龄密切相关;性别、年龄、cSBP、收缩压、舒张压是新疆哈萨克族和维吾尔族正常人群AIx的影响因素。
Background Arterial stiffness is an independent risk factor for cardiovascular disease. Central Artery Reflected Wave Enhancement Index (AIx) is an important indicator of systemic arterial stiffness, and changes in blood pressure levels have an important relationship with them. Objective To study the AIx of Kazakh and Uighur normal population in Xinjiang and analyze the related factors affecting AIx. Methods 413 Kazaks and 587 Uygur normals in Xinjiang were selected. The subjects were surveyed, general physical examination and blood glucose, blood lipids, renal function and C-reactive protein detection, central arterial systolic blood pressure (cSBP) and AIx were measured by Sphygmocor pulse wave analysis system. Results The AIx values of normal Kazak people in Xinjiang were higher than those of Uygur nationalities in Xinjiang [(28.4 ± 11.8)% vs (23.3 ± 11.5)%, P <0.05]. Correlation analysis showed that AIx was positively correlated with age (Kazak: r = 0.388 , P <0.05; Uygur: r = 0.386, P <0.05). Multivariate stepwise regression analysis showed that gender, age, cSBP, systolic blood pressure and diastolic blood pressure were the influencing factors of AIx in Kazaks of Xinjiang, while sex, age, cSBP, systolic blood pressure, diastolic blood pressure and C-reactive protein were the influencing factors of AIx in Xinjiang Uygur. Conclusion The AIx values of normal Kazak people in Xinjiang are higher than that of Uyghurs in Xinjiang and are closely related to age. Gender, age, cSBP, systolic blood pressure and diastolic blood pressure are the influencing factors of AIx in Kazakh and Uygur nationality in Xinjiang.