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为了解不同饲料硒水平对大鼠肝脏中谷胱甘肽过氧化物酶和脱碘酶活性的影响及确定它们发挥最佳活性时的最低饲料硒水平。５４只体重为５０～６０ｇ的雄性断孔Ｗｉｓｔａｒ大鼠分成９组，分别喂以９种含硒水平为０．０１，０．０２，０．０３，０．０４，０．０５，０．０６，０．１，０．２和５ｍｇ／ｋｇ的不同饲料。实验持续２０周。９组动物２０周的体重增长除５ｍｇ／ｋｇ饲料组与０．１、０．２ｍｇ／ｋｇ饲料组之间有差异外，其余均没有显著性差异。谷胱甘肽过氧化物酶的活性随着饲料硒水平的升高而升高，当饲料硒含量为０．１，０．２和５ｍｇ／ｋｇ饲料时，活性达到最高。因此它发挥正常活性范围的最低饲料硒需要量为０．１ｍｇ／ｋｇ。９个组脱碘酶的活性（ｎｍｏｌ／ｍｉｎ．ｇ）在０．０５至０．２ｍｇ／ｋｇ饲料时活性最高，在５ｍｇ／ｋｇ饲料时酶活性降低，发挥最佳活性最低饲料硒需要量为０．０５ｍｇ／ｋｇ。
To understand the effects of different dietary selenium levels on glutathione peroxidase and deiodinase activities in rat livers and to determine the lowest dietary selenium levels at which they exert optimal activity. 54 male Wistar rats weighing 50-60 g were divided into 9 groups and fed with 9 kinds of selenium containing levels of 0.01, 0.02, 0.03, 0.04, 0.05, 0.06 , 0.1, 0.2 and 5 mg / kg of different diets. The experiment lasted 20 weeks. Body weight gain in the nine groups of animals at 20 weeks was not significantly different except for differences between the 5 mg / kg diet group and 0.1 and 0.2 mg / kg diet groups. The activity of glutathione peroxidase increased with the increase of dietary selenium levels. When the dietary selenium content was 0.1, 0.2 and 5 mg / kg diet, the activity reached its peak. Therefore, it exerts the lowest active selenium requirement in the range of normal activity of 0.1mg / kg. Nine groups of deiodinase activity (nmol / min.g) at 0.05 to 0.2mg / kg feed the highest activity at 5mg / kg feed enzyme activity decreased to play the best activity of the lowest feed selenium requirement 0.05 mg / kg.