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目的探讨~(99m)Tc-MIBI亲肿瘤显像在头颈部肿瘤定性诊断中的应用价值。方法 91例临床初诊为头颈部肿瘤的患者和20例正常志愿者进行了早期和延迟的~(99m)Tc-MIBI头颈部断层显像。结果 ~(99m)Tc-MIBI早期／延迟显像诊断头颈部恶性肿瘤的总体灵敏度、特异性、准确性及阳性预测值分别为78.7％／72.3％、72.1％／ 88.4％、75.6％／80.0％和75.5％／87.2％；鼻咽癌、非霍奇金淋巴瘤显像效果优于上颌窦癌。~(99m)Tc-MIBI显像对于鼻咽癌复发／残留以及鼻腔非霍奇金淋巴瘤定性诊断价值明显优于CT和MRI检查。结论 ~(99m)Tc-MIBI亲肿瘤显像在头颈部肿瘤的定性诊断中有较好的应用前景,在判断肿瘤的范围、局部侵犯及发现颅底、颅内的转移灶等方面有独特的优势。
Objective To investigate the value of ~ (99m) Tc-MIBI tumor imaging in the qualitative diagnosis of head and neck cancer. Methods Ninety-one patients with newly diagnosed head and neck cancer and 20 normal volunteers underwent early and delayed 99m Tc-MIBI head and neck scintigraphy. Results The overall sensitivity, specificity, accuracy and positive predictive value of ~ (99m) Tc-MIBI early / late imaging in the diagnosis of head and neck cancer were 78.7% / 72.3%, 72.1% / 88.4%, 75.6% / 80.0 % And 75.5% / 87.2% respectively. The imaging results of nasopharyngeal carcinoma and non-Hodgkin’s lymphoma were better than that of maxillary sinus cancer. ~ (99m) Tc-MIBI imaging is significantly superior to CT and MRI in the diagnosis of nasopharyngeal carcinoma recurrence / residual and nasal non-Hodgkin’s lymphoma. Conclusion ~ 99m Tc-MIBI tumor imaging has a good prospect in the qualitative diagnosis of head and neck cancer. It has a unique application in judging the extent of tumor, local invasion and finding the skull base and intracranial metastases The advantages.