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目的探讨住院患者发生急性肾损伤(AKI)的发病和治疗情况及危险因素。方法对2008年12月-2011年12月在我院住院期间发生急性肾损伤32例患者的临床资料进行回顾性分析。结果诱发AKI的最常见因素是感染(43.8%)、心力衰竭(21.9%)、术后或外伤(15.6%)。在慢性肾脏病基础上发生急性肾损伤者8例,占总数的25.0%。治疗后有71.9%患者的肾功能得到完全或部分恢复。结论急性肾损伤合并多脏器衰竭、高龄及肿瘤患者病变程度较重,预后较差。感染是主要致病因素。早期积极治疗可使多数AKI患者病情发生逆转。
Objective To investigate the incidence and treatment of acute kidney injury (AKI) in hospitalized patients and its risk factors. Methods The clinical data of 32 patients with acute renal injury who were hospitalized in our hospital from December 2008 to December 2011 were retrospectively analyzed. Results The most common causes of AKI were infection (43.8%), heart failure (21.9%), postoperative or trauma (15.6%). In the chronic kidney disease on the basis of acute kidney injury in 8 cases, accounting for 25.0% of the total. After treatment, 71.9% of patients had complete or partial recovery of renal function. Conclusion Acute renal injury complicated with multiple organ failure, advanced age and cancer patients with severe lesions, the prognosis is poor. Infection is the main causative agent. Early active treatment can reverse the majority of AKI patients.