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目的探讨影响急性白血病初治诱导缓解的因素。方法总结48例急性白血病的治疗情况,分析年龄、白血病类型及外周血白细胞数与完全缓解率(CR)的关系。结果不同年龄、周围血白细胞计数的完全缓解率比较差异有统计学意义(P<0.05)。白血病类型的CR率比较差异无统计学意义(P>0.05)。结论高龄(>60岁)和高白细胞急性白血病(外周血白细胞计数>100×109/L),CR率低,预后差。
Objective To investigate the factors that affect the induction of acute leukemia in primary treatment. Methods The treatment of 48 cases of acute leukemia was summarized. The relationship between age, type of leukemia, peripheral white blood cell count and complete remission rate (CR) was analyzed. Results The complete remission rate of peripheral white blood cell count was significantly different at different ages (P <0.05). There was no significant difference in CR rate of leukemia (P> 0.05). Conclusion The elderly patients (> 60 years) and high leukocyte acute leukemia (peripheral blood leukocyte count> 100 × 109 / L) have low CR rate and poor prognosis.